加入收藏
百奥莱博公司客服电话百奥莱博QQ百奥莱博QQ百奥莱博QQ
百奥莱博公司微信服务号

产品目录

所在位置:所有产品 > 抗体抗原 > 一抗 > SNAP25抗体
SNAP25抗体图片
产品货号:
Z27017
中文名称:
SNAP25抗体
英文名称:
Anti-SNAP25 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-SNAP25 Antibody
指标别名RIC 4;RIC4;SEC9;SNAP;SNAP 25;SNAP25;SUP;Super protein
克隆性Polyclonal
检验物种human,mouse,rat
应用范围WB,IHC
基因名称SNAP25
抗体来源Rabbit
抗体类型IgG
免疫原A synthetic peptide corresponding to a sequence at the C-terminus of human SNAP25(186-200aa DSNKTRIDEANQRAT),identical to the related rat and mouse sequences.
实际分子量25KD
成分500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol.
纯化方式Immunogen affinity purified.
浓度500μg/mL
产品形态溶液
保存条件12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing.
背景资料Synaptosome-associated protein of 25,000 daltons also known as SNAP-25 is a protein which in humans encodes a 25-kD protein of 206 amino acids.It was first investigated as a neuron-specific gene preferentially expressed in mouse hippocampus.The tSNARE(the target-membrane soluble NSF-attachment protein receptor,where NSF is N-ethylmaleimide-sensitive fusion protein) synaptosomal-associated protein of 25kDa(SNAP-25) is expressed in pancreatic B-cells and its cleavage by botulinum neurotoxin E(BoNT/E) abolishes stimulated secretion of insulin.In the nervous system,two SNAP-25 isoforms(a and b) have been described,which are produced by alternative splicing.Nagy et al.(2004) identified mammalian Snap25a and Snap25b as targets of protein kinase A,a key regulator of neurosecretion that primes slowly releasable pools and readily releasable pools of secretory vesicles.SNAP-25 inhibits P/Q- and L-type voltage-gated calcium channels located presynaptically and interacts with the synaptotagmin C2B domain in Ca2+-independent fashion.In glutamatergic synapses SNAP-25 decreases the Ca2+ responsiveness,while it is naturally absent in GABAergic synapses.
Uniprot IDP60880
推荐配套试剂Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。
基因名全称synaptosomal-associated protein,25kDa
蛋白名全称Synaptosomal-associated protein 25(SNAP-25)
推荐稀释比
Western blot(WB) 1:500~2000
Immunohistochemistry in paraffin section (IHC) 1:50~400
(Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user.

相关搜索:SNAP25抗体SNAP25多抗Anti-SNAP25 Antibody
首页 |  关于我们 |  联系我们 |  在线咨询 |  网站地图
北京百奥莱博科技有限公司 京ICP备14007103号-3